Firstly, please always provide descriptive titles for your threads. What would the forum look like if everyone used "¿¿¿¿¿¿" like you?
Secondly, that red cross is the place-holder displayed by Windows when an image fails to load. You can't remove any image because there is no image to remove.
Where is this image/place-holder located? How is it being loaded? This is the sort of information you should be posting in the first place. Very few questions can be adequately asked in one short sentence like that. Remember that we have no prior knowledge of your project so give us as much relevant information as you can. How many different places could an image be in a .NET app? Should we have to guess where yours is?